Prof. Lexy von Diezmann

The Diezmann lab uses single-molecule fluorescence microscopy and targeted mutations to reverse-engineer the dynamic chemical system that regulates recombination between meiotic chromosomes. They primarily work in the germline of the transparent, genetically tractable model organism Caenorhabditis elegans. By resolving how proteins self-organize in the developing meiotic nuclei of this tiny animal, this work provides a window into the nanoscale molecular biology of transformative DNA repair.