PHARM Drug Design, Ctr for
College of Pharmacy
Twin Cities
College of Pharmacy
Twin Cities
Project Title:
Antiviral and Anticancer Drug Design
This group's work primarily focuses on design, synthesis, and bioevaluation of small organic molecules for antiviral drugs treating HIV, hepatitis B virus (HBV), cytomegalovirus (CMV), influenza, flaviviruses, and coronaviruses. They also conduct research targeting a new enzyme called TDP2, which is involved in DNA repair and implicated in cancer therapy. The group's chemistry approach on these projects often involves structure-based design of inhibitors, virtual screening, homology modeling, and other methods.
Project Investigators
Ajit Jagtap
John Liu
Samuel Offei
Won Hee Ryu
Muhammad Syafiq Shahari
Professor Zhengqiang ZQ Wang
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