Professor Rick Wagner

The goal of this laboratory is to apply the principles of chemical biology and medicinal chemistry to the design of new chemical- and cell-based therapies by:

• Applying chemical induced dimerization to guide the self-assembly of protein nanorings that can be used for drug delivery, tumor imaging, and the targeting of immune and stem cells for tumor targeting or tissue regeneration
• Designing therapeutic nucleotide prodrugs that can be targeted to and activated by diseased tissues
• Uncovering the natural function of Hint proteins and applying this knowledge to the design of anticancer, antiviral drugs, and new pain medications