Dr. Paul Robbins

These researchers work on the development of approaches to regulate immune function for treatment of autoimmune diseases, cancer and, more recently, senescence, aging, and age-related degenerative diseases. Other work includes the identification and characterization of the first senotherapeutic drugs and drug combinations currently in clinical trials and developing and optimizing pharmacologic approaches to eliminate senescent cells, which accumulate with aging. The PI also oversees a large effort at the U of M to test candidate drugs that extend healthspan in mouse models of aging, including improving metabolism and has been developing approaches to analyze spatially the presence of senescence cells in tissues.