Professor Jen Poynter

Pediatrics
Medical School
Twin Cities
Project Title: 
Molecular Epidemiology of Pediatric Germ Cell Tumors

The overarching goal of this work is to understand the molecular epidemiology of pediatric germ cell tumors (GCTs) and myeloid malignancy. This research involves comprehensively evaluating the molecular alterations in these rare tumors to discover differences across the histologic subtypes using methylation analysis, mRNA expression, genetic variation, and miRNA expression. Software including R, BWA, HISAT2, and Python is used to analyze data from genome-wide array genotyping and sequencing studies. These analyses can help uncover pathways that are important in the pathogenesis of cancer and can also be useful for identifying new therapeutic targets.

Project Investigators

Benjamin Cole
Aubrey Hubbard
Thomas Kono
John Lane
Elizabeth Lee
Dr. Erin Marcotte
Dr. Lauren Mills
Rachel Moss
Rose Neis
Professor Nathan Pankratz
Professor Jen Poynter
Andy Raduski
Jeannette Sample
Charles Silkin
Dr Shannon Sullivan
Dr. Lindsay Williams
 
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