College of Science & Engineering
Twin Cities
This lab employs and develops modern biophysical techniques to study cellular processes with high precision and detail.
Living cells have the remarkable ability to sense environmental signals such as physical force or small molecules. This information is processed by intracellular signaling networks, which allow a cell to respond to the stimulus. This group's research, at the intersection of physics and biology, aims to understand how these cellular signaling processes are regulated on different hierarchical length-scales by employing and further developing single molecule and super-resolution microscopy techniques. To gain quantitative insights into their super-resolution microscopy data, they also further develop and apply analysis techniques for large datasets including cross-correlation based methods that are computationally too intense to be performed on lab computers. MSI and in particular the supercomputers' GPUs have been a very valuable resource.