Professor Edgar Arriaga

CSENG Chemistry
College of Science & Engineering
Twin Cities
Project Title: 
Subcellular Studies of Aging

Aging is a process that has disparate effects on a population of cells, even within a single organism. This work focuses on differences in the aging process, which can be observed with better resolution at the organelle and protein level to understand the cellular impact. They are also studying the driven factor known as senescence. The researchers aim to improve upon existing techniques - such as quantitative proteomics and clustering algorithms for proteomic and transcriptomic data - and help to mature new techniques to improve understanding of how aging impacts cellular populations. This research is particularly valuable to conditions that have distinct aging components, such as the three most widespread neurodegenerative diseases of Alzheimer's, Huntington's, and Parkinson's. 

Project Investigators

Professor Edgar Arriaga
Maya Butler
Kris Elbein
Hyeokjung Kim
Yijia Li
Marissa Macchietto
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