Adam Isabella

Using zebrafish branched nerves as a model, these researchers employ genetic, genomic, embryological, and live imaging approaches to understand how single-cell decision-making is regulated and coordinated to generate large-scale patterns of innervation in the nervous system. They take a dual approach to examine how axon target selection is controlled to build patterned branched nerve structures during embryonic development, and rebuild and repattern these structures during regeneration.