August 2011

Membrane proteins play vital roles in many cellular processes such as cell fusion, signal transduction, ion translocation, and homeostasis, among others.To link structure to function, it is necessary to understand membrane protein dynamics within their native environment.The research group of Professor Gianluigi Veglia (BMBB) uses MSI resources to develop new computational approaches to model membrane protein structures and to study their dynamics in explicit lipid membranes. This image shows an NMR structure of membrane protein phospholamban (30kDa) in lipid bilayer.